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Product Name
CD276 Rabbit mAb
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Gene ID
80381
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SwissProt ID
Q5ZPR3
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Gene Name
CD276
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Alternative Names
CD276; B7H3; PSEC0249; CD276 antigen; 4Ig-B7-H3; B7 homolog 3; B7-H3; Costimulatory molecule; CD276
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Background
May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces.
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Research Field
Immunology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse
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Application
WB,FC,IP
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Dilution Ratio
WB: 1/500-1/1000 IP: 1/50 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 57 kDa; Observed MW: 100 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R02-5J6
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human CD276
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.