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Product Name
Angiotensin Converting Enzyme 1 Rabbit mAb
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Gene ID
1636
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SwissProt ID
P12821
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Gene Name
ACE
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Alternative Names
Angiotensin-converting enzyme; somatic isoform precursor; CD143 antigen; DCP; DCP1; Dipeptidyl carboxypeptidase I; Kininase II
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Background
Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.
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Research Field
Cardiovascular
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse
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Application
WB,IHC-P,FC
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 150 kDa; Observed MW: 195 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R03-4M7
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human ACE1
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.