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Product Name
Claudin 1 Rabbit mAb
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Gene ID
9076
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SwissProt ID
O95832
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Gene Name
CLDN1
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Alternative Names
CLDN1; CLD1; SEMP1; Claudin-1; Senescence-associated epithelial membrane protein
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Background
The claudin family is composed of 23 integral membrane proteins, and their expression, which varies among tissue types, may determine both the strength and properties of the epithelial barrier. Alteration in claudin protein expression pattern is associated with several types of cancer. Claudin-1 is expressed primarily in keratinocytes and normal mammary epithelial cells, but is absent or reduced in breast carcinomas and breast cancer cell lines.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 23 kDa; Observed MW: 18-22 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R09-5K9
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human Claudin 1
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.