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Product Name
Presenilin 1 Rabbit mAb
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Gene ID
5663
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SwissProt ID
P49768
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Gene Name
PSEN1
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Alternative Names
PSEN1; AD3; PS1; PSNL1; Presenilin-1; PS-1; Protein S182
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Background
Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity.
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Research Field
Neuroscience
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,FC
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Dilution Ratio
WB: 1/500-1/1000 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 53 kDa; Observed MW: 35 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R01-3J6
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human Presenilin 1
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.