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Product Name
YY1 Rabbit mAb
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Gene ID
7528
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SwissProt ID
P25490
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Gene Name
YY1
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Alternative Names
YY1; Delta transcription factor; INO80 complex subunit S; NF-E1; Yin and yang 1; YY-1
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Background
Its activity is regulated by transcription factors and cytoplasmic proteins that have been shown to abrogate or completely inhibit YY1-mediated activation or repression. For example, it acts as a repressor in absence of adenovirus E1A protein but as an activator in its presence. Acts synergistically with the SMAD1 and SMAD4 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,IP
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Dilution Ratio
WB: 1/500-1/1000 IP: 1/20
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Molecular Weight
Calculated MW: 45 kDa; Observed MW: 65 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R02-8A3
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Isotype
IgG
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Immunogen
A synthetic peptide of human YY1
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.