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Product Name
YAP1 Rabbit mAb
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Gene ID
10413
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SwissProt ID
P46937
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Gene Name
YAP1
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Alternative Names
YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65
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Background
YAP (Yes-associated protein, YAP65) was identified based on its ability to associate with the SH3 domain of Yes. Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse
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Application
WB,ICC/IF
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200
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Molecular Weight
Calculated MW: 54 kDa; Observed MW: 70-75 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R06-5E9
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Isotype
IgG
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Immunogen
A synthetic peptide of human YAP1
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.