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Product Name
XPD Rabbit mAb
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Gene ID
2068
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SwissProt ID
P18074
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Gene Name
ERCC2
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Alternative Names
BTF2 p80; COFS2; CXPD; EM9; ERCC2; MAG; TFIIH p80; TTD; XPD; XPDC
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Background
ATP-dependent 5'-3' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,ICC/IF
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200
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Molecular Weight
Calculated MW: 87 kDa; Observed MW: 80 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R08-2I3
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Isotype
IgG
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Immunogen
A synthetic peptide of human XPD
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.