-
Product Name
XIAP Rabbit mAb
-
Gene ID
11798
-
SwissProt ID
Q60989
-
Gene Name
Xiap
-
Alternative Names
API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3
-
Background
Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis. Acts as a direct caspase inhibitor. Directly bind to the active site pocket of CASP3 and CASP7 and obstructs substrate entry. Inactivates CASP9 by keeping it in a monomeric, inactive state.
-
Research Field
Cell Biology
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human,Mouse,Rat
-
Application
WB
-
Dilution Ratio
WB: 1/500-1/1000
-
Molecular Weight
Calculated MW: 56 kDa; Observed MW: 53 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
R02-9A3
-
Isotype
IgG
-
Immunogen
Recombinant protein of mouse XIAP
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.