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Product Name
WDR5 Rabbit mAb
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Gene ID
11091
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SwissProt ID
P61964
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Gene Name
WDR5
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Alternative Names
WDR5; BIG3; WD repeat-containing protein 5; BMP2-induced 3-kb gene protein
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Background
Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 37 kDa; Observed MW: 37 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R05-4D3
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Isotype
IgG
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Immunogen
A synthetic peptide of human WDR5
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.