-
Product Name
HIF1AN Rabbit mAb
-
Gene ID
55662
-
SwissProt ID
Q9NWT6
-
Gene Name
HIF1AN
-
Alternative Names
FIH 1; FIH1; HIF1AN
-
Background
Hydroxylates HIF-1 alpha at 'Asp-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator.
-
Research Field
Epigenetics and Nuclear Signaling
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human
-
Application
WB,IHC-P,ICC/IF,FC
-
Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100
-
Molecular Weight
Calculated MW: 40 kDa; Observed MW: 40 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
R06-6P8
-
Isotype
IgG
-
Immunogen
A synthesized peptide derived from human HIF1AN
-
Purification
Affinity Chromatography
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.