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Product Name
DIAPH1 Rabbit mAb
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Gene ID
1729
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SwissProt ID
O60610
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Gene Name
DIAPH1
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Alternative Names
DIAPH1; DFNA1; DIA1; DIAP1; DIAPH1; DRF1; hDIA1; LFHL1
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Background
Acts in a Rho-dependent manner to recruit PFY1 to the membrane. Required for the assembly of F-actin structures, such as actin cables and stress fibers. Nucleates actin filaments. Binds to the barbed end of the actin filament and slows down actin polymerization and depolymerization. Required for cytokinesis, and transcriptional activation of the serum response factor.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,IHC-P,ICC/IF
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
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Molecular Weight
Calculated MW: 141 kDa; Observed MW: 155 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R02-6J4
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human DIAPH1
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.