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Product Name
TINF2 Rabbit mAb
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Gene ID
26277
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SwissProt ID
Q9BSI4
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Gene Name
TINF2
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Alternative Names
DKCA3; Tin 2; TIN2; TINF 2; Tinf2
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Background
Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 50 kDa; Observed MW: 40 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R02-8L2
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human Tin2
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.