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Product Name
Phospho-c-Jun (Ser73)+JunD (Ser100) Rabbit mAb
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Gene ID
3725/3727
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SwissProt ID
P05412,P17535
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Gene Name
JUN/JUND
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Alternative Names
JunD; c-Jun;
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Background
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3' (PubMed:10995748, PubMed:22083952). Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation (PubMed:17210646). Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306).
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse
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Application
WB,IHC-P,IP
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/100-1/200 IP: 1/50
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Molecular Weight
Calculated MW: 36 kDa;Observed MW:38,42,45kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R27-9A-9
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human Phospho-c-Jun (S73)+JunD (S100)
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Phosphorylated
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Form
Liquid
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Buffer System
Liquid in PBS , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.