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Product Name
Phospho-TAOK1/2/3 (Ser181 + Ser181 + Ser177) Rabbit mAb
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Gene ID
51347/57551/9344
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SwissProt ID
Q7L7X3/Q9UL54/Q9H2K8
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Gene Name
TAOK1/TAOK2/TAOK3
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Alternative Names
TAOK1; TAOK2; TAOK3;
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Background
Serine/threonine-protein kinase involved in different processes such as membrane blebbing and apoptotic bodies formation DNA damage response and MAPK14/p38 MAPK stress-activated MAPK cascade. Phosphorylates itself, MBP, activated MAPK8, MAP2K3, MAP2K6 and tubulins. Activates the MAPK14/p38 MAPK signaling pathway through the specific activation and phosphorylation of the upstream MAP2K3 and MAP2K6 kinases.
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/100-1/200
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Molecular Weight
Calculated MW: 116 kDa;Observed MW:140,130,110kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R32-3H-4
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human Phospho-TAOK1/2/3 (S181 + S181 + S177)
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Phosphorylated
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Form
Liquid
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Buffer System
Liquid in PBS , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.