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Product Name
ATAD2 Rabbit mAb
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Gene ID
29028
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SwissProt ID
Q6PL18
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Gene Name
ATAD2
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Alternative Names
ANCCA; Atad2; CT137; L16; PRO2000
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Background
May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,ICC/IF,FC
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 159 kDa; Observed MW: 180 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R05-5M5
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human ATAD2
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.