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Product Name
Phospho-KAP1 (Ser824) Rabbit mAb
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Gene ID
10155
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SwissProt ID
Q13263
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Gene Name
TRIM28
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Alternative Names
KAP 1; KRAB associated protein 1; KRIP1; RNF96; TF1B; TIF1 beta; TIF1B; Trim28; Tripartite motif containing 28;
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Background
Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,IP
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Dilution Ratio
WB: 1/500-1/1000 IP: 1/50
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Molecular Weight
Calculated MW:89kDa;Observed MW:110kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R16-8K-7
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human KAP1
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Phosphorylated
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Form
Liquid
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Buffer System
Liquid in PBS , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.