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Product Name
Thrombomodulin Rabbit mAb
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Gene ID
21824
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SwissProt ID
P15306
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Gene Name
Thbd
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Alternative Names
CD141; Fetomodulin; THBD; THRM; thrombomodulin; TM
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Background
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
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Research Field
Cardiovascular
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Mouse,Rat
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 62 kDa; Observed MW: 95 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R02-1G1
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Isotype
IgG
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Immunogen
Recombinant protein of mouse Thrombomodulin
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.