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Product Name
TCEA1 Rabbit mAb
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Gene ID
6917
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SwissProt ID
P23193
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Gene Name
TCEA1
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Alternative Names
SII; TCEA; TF2S; GTF2S; TFIIS
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Background
Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.MiscellaneousS-II binds to RNA-polymerase II in the absence of transcription.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 34 kDa; Observed MW: 34 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R07-9E4
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Isotype
IgG
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Immunogen
Recombinant protein of human TCEA1
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.