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Product Name
Superoxide Dismutase 1 Rabbit mAb
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Gene ID
6647
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SwissProt ID
P00441
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Gene Name
SOD1
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Alternative Names
SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1
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Background
SOD1, Cu/Zn superoxide dismutase, is a major antioxidant enzyme that catalyzes the conversion of superoxide anion to hydrogen peroxide and molecular oxygen. The mechanism by which mutant SOD1 induces the neurodegeneration observed in ALS is still unclear. Mutant SOD1 proteins become misfolded and consequently oligomerize into high molecular weight species that aggregate and end up in proteinaceous inclusions.
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,IHC-P
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Cited
WB (Duck)
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 16 kDa; Observed MW: 16 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R07-1G6
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Isotype
IgG
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Immunogen
A synthetic peptide of human Superoxide Dismutase 1
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.