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Product Name
Clusterin Rabbit mAb
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Gene ID
1191
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SwissProt ID
Q06890
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Gene Name
CLU
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Alternative Names
AAG4; Aging-associated gene 4 protein; APOJ; ApoJalpha; ApoJbeta; Apolipoprotein J; CLI; CLU; Clusterin alpha chain; Clusterin; Complement cytolysis inhibitor a chain; Complement cytolysis inhibitor; Complement cytolysis inhibitor b chain; complement lysis inhibitor; Ku70-binding protein 1; KUB1; NA1/NA2; SGP2; sulfated glycoprotein 2; Testosterone-repressed prostate message 2; TRPM2;
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Background
Isoform 1:Functions as extracellular chaperone that prevents aggregation of non native proteins (PubMed:11123922, PubMed:19535339).Prevents stress-induced aggregation of blood plasma proteins (PubMed:11123922, PubMed:12176985, PubMed:17260971, PubMed:19996109).Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro) (PubMed:12047389, PubMed:17412999, PubMed:17407782).
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Research Field
Immunology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Mouse,Rat
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Application
WB,IHC-P,IP
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/100-1/200 IP: 1/50
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Molecular Weight
Calculated MW: 52 kDa;Observed MW:40kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R93-8K-4
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human Clusterin
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.