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Product Name
SPI1 Rabbit mAb
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Gene ID
6688
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SwissProt ID
P17947
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Gene Name
SPI1
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Alternative Names
SPI1; Transcription factor PU.1; 31 kDa-transforming protein
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Background
Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing.
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Research Field
Immunology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,IHC-P,FC
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 31 kDa; Observed MW: 42 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R04-8J2
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human PU.1/Spi1
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.