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Product Name
Insulin Receptor Rabbit mAb
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Gene ID
3643
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SwissProt ID
P06213
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Gene Name
INSR
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Alternative Names
CD220; HHF5; human insulin receptor; Insr; Insulin receptor subunit beta; IR 1; IR
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Background
Insulin Receptor is a transmembrane receptor tyrosine kinase that is widely expressed in many cell lines and cell types within fetal and postnatal tissues; Insulin binding to IR induces phosphorylation of intracellular tyrosine kinase domains and recruitment of multiple SH2 and SH3 domain-containing intracellular proteins that serve as signaling intermediates for pleiotropic effects of insulin.
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Rat
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Application
WB,ICC/IF
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200
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Molecular Weight
Calculated MW: 156 kDa; Observed MW: 95 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R06-3I9
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human Insulin Receptor
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.