-
Product Name
MonoMethyl-Histone H2B (Lys116) Rabbit mAb
-
Gene ID
8349
-
SwissProt ID
Q16778
-
Gene Name
H2BC21
-
Alternative Names
Histone H2B;
-
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
-
Research Field
Epigenetics and Nuclear Signaling
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human,Mouse,Rat
-
Application
WB,IHC-P,ICC/IF
-
Dilution Ratio
WB: 1/500-1/1000 IHC: 1/100-1/200 IF: 1/50-1/200
-
Molecular Weight
Calculated MW: 14kDa;Observed MW:14kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
R96-4G-1
-
Isotype
IgG
-
Immunogen
A synthesized peptide derived from human Histone H2B (mono methyl K116)
-
Purification
Affinity Chromatography
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Liquid in PBS , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.