-
Product Name
Bcl10 Rabbit mAb
-
Gene ID
8915
-
SwissProt ID
O95999
-
Gene Name
BCL10
-
Alternative Names
BCL10; CIPER; CLAP; B-cell lymphoma/leukemia 10; B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; CIPER; Cellular homolog
-
Background
Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1.
-
Research Field
Cell Biology
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human
-
Application
WB,ICC/IF,IP
-
Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/50
-
Molecular Weight
Calculated MW: 26 kDa; Observed MW: 26 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
R07-5J9
-
Isotype
IgG
-
Immunogen
A synthesized peptide derived from human Bcl10
-
Purification
Affinity Chromatography
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.