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Product Name
LDL Receptor Rabbit mAb
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Gene ID
3949
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SwissProt ID
P01130
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Gene Name
LDLR
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Alternative Names
FH; FHC; LDL receptor; LDLCQ2; LDLR; Low Density Lipoprotein Receptor; Low density lipoprotein receptor class A domain containing protein 3
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Background
Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.
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Research Field
Cardiovascular
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 95 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R04-3E7
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human LDL Receptor
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.