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Product Name
KMT5A Rabbit mAb
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Gene ID
387893
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SwissProt ID
Q9NQR1
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Gene Name
KMT5A
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Alternative Names
KMT5A; PR-Set7; SET07; SET8
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Background
Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,FC
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Dilution Ratio
WB: 1/500-1/1000 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 43 kDa; Observed MW: 50 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R05-7N6
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human KMT5A / SETD8 / Pr-SET7
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.