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Product Name
Trk B Rabbit mAb
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Gene ID
18212
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SwissProt ID
P15209
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Gene Name
Ntrk2
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Alternative Names
Tkrb; trkB; trk-B; GP145-TrkB/GP95-TrkB
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Background
Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2.
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Research Field
Neuroscience
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Mouse,Rat
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Application
WB,IHC-P,IP
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
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Molecular Weight
Calculated MW: 92 kDa; Observed MW: 90-140 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R03-4C7
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Isotype
IgG
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Immunogen
Recombinant protein of mouse TrkB
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.