-
Product Name
PD-L1 Rabbit mAb
-
Gene ID
29126
-
SwissProt ID
Q9NZQ7
-
Gene Name
CD274
-
Alternative Names
B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1; CD274;
-
Background
Programmed cell death ligand 1(CD274, or B7-H1, PD-L1), is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors, the B7s are key regulators of the adaptive immune response. CD274 is suggested a negative regulator of T and B cell, and play important role in mediating tolerance of lymphocytes to self-antigens.
-
Research Field
Immunology
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human,Mouse,Rat
-
Application
WB,IHC-P
-
Dilution Ratio
WB: 1/500-1/1000 IHC: 1/100-1/200
-
Molecular Weight
Calculated MW:33kDa;Observed MW:46kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
R31-1P-3
-
Isotype
IgG
-
Immunogen
A synthesized peptide derived from human PD-L1 (CD274)
-
Purification
Affinity Chromatography
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Liquid in PBS , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.