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Product Name
JNK1/3 Rabbit mAb
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Gene ID
5599/5602
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SwissProt ID
P45983/P53779
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Gene Name
MAPK8/MAPK10
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Alternative Names
c-Jun N-terminal kinase 3; FLJ12099; FLJ33785; JNK1; JNK3; JNK3 alpha protein kinase; JNK3A; MAP kinase 10; MAP kinase p49 3F12; MAPK 10; MAPK10;
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Background
The stress-activated protein kinase/Jun-amino-terminal kinase SAPK/JNK is potently and preferentially activated by a variety of environmental stresses including UV and gamma radiation, ceramides, inflammatory cytokines, and in some instances, by growth factors and GPCR agonists. As with the other MAPKs, the core signaling unit is composed of a MAPKKK, typically MEKK1-MEKK4, or by one of the mixed lineage kinases (MLKs), which phosphorylate and activate MKK4/7.
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,IP
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Dilution Ratio
WB: 1/500-1/1000 IP: 1/50
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Molecular Weight
Calculated MW: 48 kDa;Observed MW:46,54kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R18-8H-4
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human JNK1/JNK3
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.