-
Product Name
ERK1 Rabbit mAb
-
Gene ID
5595
-
SwissProt ID
P27361
-
Gene Name
MAPK3
-
Alternative Names
MAPK3
-
Background
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
-
Research Field
Cell Biology
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human
-
Application
WB,IHC-P,IP
-
Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
-
Molecular Weight
Calculated MW: 43 kDa; Observed MW: 43 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
R08-3C6
-
Isotype
IgG
-
Immunogen
A synthetic peptide of human ERK1
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.