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Product Name
ZIC 1 Rabbit mAb
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Gene ID
7545
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SwissProt ID
Q15915
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Gene Name
ZIC1
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Alternative Names
ZIC; Zic protein member 1; Zinc finger protein 201; Zinc finger protein ZIC1; ZNF201
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Background
Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Involved in the spatial distribution of mossy fiber (MF) neurons within the pontine gray nucleus (PGN). Plays a role in the regulation of MF axon pathway choice. Promotes MF migration towards ipsilaterally-located cerebellar territories.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,ICC/IF,FC
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 48 kDa; Observed MW: 48 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R09-4A6
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human Zic1
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.