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Product Name
SOX2 Rabbit mAb
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Gene ID
6657
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SwissProt ID
P48431
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Gene Name
SOX2
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Alternative Names
SOX2; ANOP3; MCOPS3; MGC2413; lcc; SRY related HMG box 2;
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Background
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
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Research Field
Neuroscience
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse
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Application
WB,IHC-P,ICC/IF
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/100-1/200 IF: 1/50-1/200
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Molecular Weight
Calculated MW: 34 kDa;Observed MW:34kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R74-1A-2
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human SOX2
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.