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Product Name
Cytochrome P450 3A4 Rabbit mAb
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Gene ID
1576
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SwissProt ID
P08684
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Gene Name
CYP3A4
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Alternative Names
HLP; CP33; CP34; CYP3A; NF-25; CYP3A3; P450C3; CYPIIIA3; CYPIIIA4; P450PCN1; CYP3A4
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Background
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. The enzyme also hydroxylates etoposide.
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Research Field
Cardiovascular
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,IHC-P,IP
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/50
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Molecular Weight
Calculated MW: 57 kDa; Observed MW: 57 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R07-8F6
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human Cytochrome P450 3A4
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.