-
Product Name
Phospho-Histone H2A.X (Ser139) Rabbit mAb
-
Gene ID
3014
-
SwissProt ID
P16104
-
Gene Name
H2AX
-
Alternative Names
H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X; gamma H2A.X
-
Background
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
-
Research Field
Epigenetics and Nuclear Signaling
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human,Mouse,Rat
-
Application
WB,IHC-P,ICC/IF,IP
-
Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/30
-
Molecular Weight
Calculated MW: 15 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
R03-2Z1
-
Isotype
IgG
-
Immunogen
A synthesized peptide derived from human Phospho-Histone H2A.X (S139)
-
Purification
Affinity Chromatography
-
Conjugation
Unconjugated
-
Modification
Phosphorylated
-
Form
Liquid
-
Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.