-
Product Name
ITK Rabbit mAb
-
Gene ID
3702
-
SwissProt ID
Q08881
-
Gene Name
ITK
-
Alternative Names
ITK; EMT; LYK; Tyrosine-protein kinase ITK/TSK; Interleukin-2-inducible T-cell kinase; IL-2-inducible T-cell kinase; Kinase EMT; T-cell-specific kinase; Tyrosine-protein kinase Lyk
-
Background
Interleukin-2 inducible T-cell kinase (Itk, Emt or Tsk) is a member of the non-receptor protein tyrosine kinases. Family members of Itk include Tec, Btk, Rlk and Bmx and are all defined by a common structure: an amino-terminal PH domain, a Tec-homology domain and a SH3 and SH2 domain followed by a carboxy-terminal kinase domain. Tec, Rlk and Itk are expressed in T cells and activated in response to T cell receptor (TCR) engagement.
-
Research Field
Signal Transduction
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human
-
Application
WB,IHC-P,FC
-
Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 FC: 1/50-1/100
-
Molecular Weight
Calculated MW: 72 kDa; Observed MW: 72 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
R04-8H3
-
Isotype
IgG
-
Immunogen
A synthesized peptide derived from human ITK
-
Purification
Affinity Chromatography
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.