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Product Name
Acetyl-p53 (Lys370) Rabbit mAb
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Gene ID
7157
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SwissProt ID
P04637
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Gene Name
TP53
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Alternative Names
P53; BCC7; LFS1; TRP53
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Background
Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,ICC/IF,IP
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
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Molecular Weight
Calculated MW: 44 kDa; Observed MW: 53 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R06-7C9
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Isotype
IgG
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Immunogen
A synthetic acetyl-peptide corresponding to residues surrounding Lys370 of human p53
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Acetylated
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.