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Product Name
RING2 Rabbit mAb
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Gene ID
6045
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SwissProt ID
Q99496
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Gene Name
RNF2
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Alternative Names
BAP1; DING; BAP-1; HIPI3; RING2; RING1B
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Background
E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 38 kDa; Observed MW: 38 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R04-2B3
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human RING2 / RING1B / RNF2
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.