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Product Name
RPE65 Rabbit mAb
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Gene ID
6121
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SwissProt ID
Q16518
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Gene Name
RPE65
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Alternative Names
LCA2; mRPE65; p63; rd12; Retinal pigment epithelium specific 61 kDa protein; RP20; RPE65; sRPE65
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Background
Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol.
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Research Field
Tags & Cell Markers
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,IP
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Dilution Ratio
WB: 1/500-1/1000 IP: 1/50
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Molecular Weight
Calculated MW: 61 kDa; Observed MW: 61 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R07-1E1
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human RPE65
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.