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Product Name
Alpha-2-Macroglobulin Rabbit mAb
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Gene ID
2
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SwissProt ID
P01023
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Gene Name
A2M
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Alternative Names
Alpha-2-Macroglobulin; A2m; Alpha 2M; Alpha-2-macroglobulin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; CPAMD5; FWP007; S863 7
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Background
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
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Research Field
Cardiovascular
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Product Categories
Recombinant Rabbit Monoclonal antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 163 kDa; Observed MW: 163 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R02-9D9
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human A2M
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.