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Product Name
MonoMethyl-Histone H3 (Lys14) Rabbit mAb
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Gene ID
8290
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SwissProt ID
Q16695
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Gene Name
H3-4
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Alternative Names
H3K14me; H3.4; H3/g; H3FT; H3t
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Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse
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Application
WB,ICC/IF
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200
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Molecular Weight
Calculated MW: 16 kDa; Observed MW: 16 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R03-7N4
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Isotype
IgG
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Immunogen
A synthetic peptide of human MonoMethyl-Histone H3-K14
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Methylated
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.