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Product Name
Ubiquitin Protein Ligase E3A Rabbit mAb
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Gene ID
7337
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SwissProt ID
Q05086
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Gene Name
UBE3A
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Alternative Names
Ubiquitin-protein ligase E3A; UBE3A; E6AP; EPVE6AP; HPVE6A
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Background
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the RAD23A and RAD23B, MCM7 (which is involved in DNA replication), annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,ICC/IF,IP
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
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Molecular Weight
Calculated MW: 101 kDa; Observed MW: 101 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R02-1A0
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Isotype
IgG
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Immunogen
Recombinant protein of human UBE3A
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.