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Product Name
Ubiquitin Conjugating Enzyme E2 N Rabbit mAb
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Gene ID
7334
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SwissProt ID
P61088
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Gene Name
UBE2N
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Alternative Names
BLU; HEL-S-71; Ubc13; UbCH ben; UbcH13; UBCHBEN; Ube2n
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Background
The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. This type of polyubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Rat
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Application
WB,ICC/IF
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200
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Molecular Weight
Calculated MW: 17 kDa; Observed MW: 17 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R05-5B0
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Isotype
IgG
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Immunogen
A synthetic peptide of human Ube2N/Ubc13
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.