产品详情
-
Product Name
NOXA Rabbit mAb
-
Gene ID
5366
-
SwissProt ID
Q13794
-
Gene Name
PMAIP1
-
Alternative Names
APR; ATL-derived; NOXA; Pmaip1; Protein Noxa
-
Background
Noxa is a pro-apoptotic Bcl-2 family protein that contains a single Bcl-2 homology (BH3) domain. Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1.
-
Research Field
Cell Biology
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human
-
Application
WB
-
Dilution Ratio
WB: 1/500-1/1000
-
Molecular Weight
Calculated MW: 6 kDa; Observed MW: 16 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
R01-5G3
-
Isotype
IgG
-
Immunogen
A synthesized peptide derived from human Noxa
-
Purification
Affinity Chromatography
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用,请参照上方的缩写含义,仔细对照后选择合适的产品。