-
Product Name
Toll-Like Receptor 5 Rabbit mAb
-
Gene ID
7100
-
SwissProt ID
O60602
-
Gene Name
TLR5
-
Alternative Names
Toll-Like Receptor 5; SLEB1; TIL3; Tlr5; Toll like receptor 5 precursor
-
Background
Six human homologs of the Drosophila Toll receptor were initially identified based on their sequence similarities and designated toll-like receptors (TLR). Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
-
Research Field
Immunology
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human,Mouse,Rat
-
Application
WB
-
Dilution Ratio
WB: 1/500-1/1000
-
Molecular Weight
Calculated MW: 98 kDa; Observed MW: 98 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
R01-3A3
-
Isotype
IgG
-
Immunogen
A synthesized peptide derived from human TLR5
-
Purification
Affinity Chromatography
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.