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Product Name
LIN28 Rabbit mAb
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Gene ID
79727/389421
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SwissProt ID
Q9H9Z2/Q6ZN17
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Gene Name
LIN28A/LIN28B
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Alternative Names
Protein lin-28 homolog A; LIN28A; CSDD1; LIN28; ZCCHC1
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Background
Involved in the timing of developmental events and choice of stage specific cell fates. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7.
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Research Field
Neuroscience
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,FC,IP
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Dilution Ratio
WB: 1/500-1/1000 IP: 1/50 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 23 kDa; Observed MW: 26 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R03-6H1
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human Lin28
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.