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Product Name
HDAC7 Rabbit mAb
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Gene ID
51564
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SwissProt ID
Q8WUI4
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Gene Name
HDAC7
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Alternative Names
HDAC7; HDAC7A; Histone deacetylase 7; HD7; Histone deacetylase 7A; HD7a
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Background
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,FC
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Dilution Ratio
WB: 1/500-1/1000 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 103 kDa; Observed MW: 124 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R08-7H7
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human HDAC7
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.