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Product Name
SOX1 Rabbit mAb
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Gene ID
6656
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SwissProt ID
O00570
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Gene Name
SOX1
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Alternative Names
Sex determining region Y box 1; sox1; SRY; SRY box containing gene 1; SRY related HMG box gene 1; Transcription factor Sox-1
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Background
Sox (Sry-related box) genes encode a family of transcription factors that play a myriad of roles in developmental processes. Sox1 and Sox2 are the earliest markers that identify neuroectodermal tissue, and these markers, together with Sox9 collectively mark neuronal stem cells (NSC's) that are present in neurogenically active areas of the mature rodent brain. Sox1 is thought to maintain the cell cycle and promote self renewal in NSCs.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse
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Application
WB,IHC-P,ICC/IF
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
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Molecular Weight
Calculated MW: 39 kDa; Observed MW: 39 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R08-8C4
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human SOX1
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.