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Product Name
Alpha B Crystallin Rabbit mAb
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Gene ID
1410
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SwissProt ID
P02511
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Gene Name
CRYAB
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Alternative Names
HspB5, CRYAB, CRYA2, HSPB5
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Background
Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Mouse,Rat
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Application
WB,IHC-P
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Dilution Ratio
WB：1/500-1/1000 IHC-P：1/50-1/100
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Molecular Weight
Calculated MW: 20 kDa; Observed MW:22 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R06-4Z-5
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Isotype
IgG
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Immunogen
Peptide
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Purification
Protein A
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS, Glycerol and BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.