产品详情
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Product Name
FOXA1 Rabbit mAb
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Gene ID
3169
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SwissProt ID
P55317
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Gene Name
FOXA1
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Alternative Names
HNF3A, TCF3A
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Background
Forkhead transcription factor (FOXA1) is a pioneering factor in the development of some organs and certain cancers. It opens tight chromatin by interacting with nucleosomal core histones. FOXA1 can bind to cis-acting elements and recruit other transcription factors to induce transcription. FOXA1 is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues, and participates in the development of a variety of endoderm-derived organ systems, such as liver, pancreas, lung and prostate. FOXA1 is related to many diseases and plays a role in hormone-dependent diseases such as breast cancer and prostate cancer.
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Research Field
Tumor biology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB
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Dilution Ratio
WB：1/500-1/1000
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Molecular Weight
Calculated MW: 49 kDa; Observed MW:52 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R08-5L-8
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Isotype
IgG
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Immunogen
Peptide
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Purification
Protein A
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS, Glycerol and BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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