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Product Name
Keratin 20 Rabbit mAb
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Gene ID
54474
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SwissProt ID
P35900
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Gene Name
KRT20
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Alternative Names
CK-20, KRT20, Cytokeratin-20
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Background
Keratin (cytokeratin) is an intermediate filament protein, which is mainly expressed in epithelial cells such as gastric epithelium and intestinal epithelium. Keratin heterodimers composed of acidic keratin (or type I keratin, keratin 9 to 23) and basic keratin (or type II keratin, keratin 1 to 8) assemble to form filaments. Keratin isoforms exhibit tissue- and differentiation-specific characteristics, making them useful as research biomarkers. Studies have shown that mutations in the keratin gene are related to skin diseases, liver and pancreatic diseases, and inflammatory bowel disease. Therefore, cytokeratin can be used as a tumor immunohistochemical marker.Keratin 20 (CK-20) is an essential intermediate filament component and the main cytoskeleton keratin of the intestinal epithelium. Studies have shown that keratin 20 is an important marker for colon cancer, liver cancer, and stomach cancer.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,IHC-P,ICC/IF,FC
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Dilution Ratio
WB：1/500-1/1000，IHC-P：1/50-1/100，ICC/IF：1/50，FC：1/50-1/100
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Molecular Weight
Calculated MW: 48 kDa; Observed MW:48 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R08-8V-8
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Isotype
IgG
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Immunogen
Peptide
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Purification
Protein A
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS, Glycerol and BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.